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Providing evidence to improve practice

Individual study: Following treatment with chloramphenicol ointment one previously infected Archey’s frog Leiopelma archeyi tested negative for chytridiomycosis

Published source details

Bishop P.J., Speare R., Poulter R., Butler M., Speare B.J., Hyatt A., Olsen V. & Haigh A. (2009) Elimination of the amphibian chytrid fungus Batrachochytrium dendrobatidis by Archey's frog Leiopelma archeyi. Diseases of Aquatic Organisms, 84, 9-15

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Use antibacterial treatment to reduce chytridiomycosis infection Amphibian Conservation

A study in a laboratory in New Zealand (Bishop et al. 2009) found that treatment of one Archey’s frog Leiopelma archeyi with an antibiotic ointment cured it of chytridiomycosis. At the end of five days’ treatment with chloramphenicol ointment, the infection was significantly reduced (zoospore equivalents: 176–217 to 7). Over the following three months the frog tested negative for chytridiomycosis in five tests. Chloramphenicol treatment did not appear to have any effect on weight, behaviour or health. The frog had 5 mg of chloramphenicol ointment applied to its back for five days. Four other wild caught frogs had chloramphenicol in water (10 mg/L) added to their containers. Containers were disinfected with 70% ethanol and the treatment solution changed daily for five days. They were tested for the chytrid fungus on arrival, at 2, 4, 8, 14 and 19 weeks and at the end of the trial. Behaviour, food consumption and weight gain was monitored daily.