Action: Treat bats for infection with white-nose syndrome
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- One study evaluated the effects of treating bats with a probiotic bacterium to reduce white-nose syndrome infection. The study was in Canada.
COMMUNITY RESPONSE (0 STUDIES)
POPULATION RESPONSE (1 STUDY)
- Survival (1 study): One randomized, replicated, controlled study in Canada found that treating little brown bats with a probiotic bacterium at the time of infection with white-nose syndrome increased survival, but treating bats 21 days prior to infection had no effect.
- Condition (1 study): One randomized, replicated, controlled study in Canada found that treating little brown bats with a probiotic bacterium at the time of infection with white-nose syndrome reduced the symptoms of the disease, but treating bats 21 days prior to infection made symptoms worse.
BEHAVIOUR (0 STUDIES)
Various treatments for bats infected with white-nose syndrome have been suggested including antifungal agents, antimicrobial and enzyme inhibitors, and ultraviolet light. Some treatments have been tested on the white-nose syndrome fungus Pseudogymnoascus destructans in laboratories (e.g. Cornelison et al. 2014, Palmer et al. 2018), but we found only one study that tested a treatment on infected bats in a laboratory.
Cornelison C.T., Keel M.K., Gabriel K.T., Barlament C.K., Tucker T.A., Pierce G.E. & Crow S.A. (2014) A preliminary report on the contact-independent antagonism of Pseudogymnoascus destructans by Rhodococcus rhodochrous strain DAP96253. BMC Microbiology, 14, 246.
Palmer J.M., Drees K.P., Foster J.T. & Lindner D.L. (2018) Extreme sensitivity to ultraviolet light in the fungal pathogen causing white-nose syndrome of bats. Nature Communications, 9, 35.
Supporting evidence from individual studies
A randomized, replicated, controlled study in 2013–2015 in a laboratory in Manitoba, Canada (Cheng et al. 2017) found that treating bats with a probiotic bacterium Pseudomonas fluorescens at the time of, but not 21 days prior, to infection with white-nose syndrome reduced symptoms and increased survival. For bats that received the probiotic treatment at the time of white-nose syndrome infection, four of five disease symptoms were lower than for untreated, infected control bats (data reported as statistical model results). For bats that received the treatment 21 days prior to infection, all five symptoms were greater than for untreated, infected control bats. Bats that received the probiotic treatment at the time of infection also had higher survival rates (71% of bats survived after 185 days) than untreated, infected control bats (18% of bats survived). Survival rates between all other treatment groups did not differ significantly. Eighty-five little brown bats Myotis lucifugus were collected from a hibernaculum and equally divided into five treatment groups (probiotic treatment 21 days prior to white-nose syndrome infection, probiotic treatment at time of infection, probiotic treatment only, infection with white-nose syndrome only, no treatment). Bats were monitored for up to 185 days during hibernation.